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Functional Medicine

Low Dose Naltrexone (LDN)

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Low Dose Naltrexone (LDN) is a treatment that encourages the body to produce its own feel-good transmitters like endorphins through a negative feedback mechanism.

These endorphins are able to either help boost the immune system where it is low, like in cancers or HIV; or it modulates the immune system where it is hyperreactive like in autoimmune conditions including gut issues. This means that the body now has enough of the right kind of ‘soldiers’ to target and solve health issues using its own innate intelligence. LDN has been used for a wide range of health concerns in patients with autoimmune diseases, cancers, HIV, MS, SLE, Crohn’s and ulcerative colitis amongst others.

Get in touch to find out more

How can LDN help you?

“The turnaround with LDN has been nothing short of miraculous, and a real game changer. After 4 months, the turnaround has been dramatic. I can sleep for 9 - 11 hours, of good quality sleep (8 out of 10), and things are improving at a faster rate. Energy levels are higher, brain fog has lifted, and most dramatic of all, my mood has improved 100%. I no longer feel depressed, despite being sub-optimal. I wake up happier, relaxed, and with a positive mindset, excited about the future.
The key to LDN was definitely perseverance. Each stage caused initial upset, and then the reward phase followed. The big pay off being 4 months down the line. Definitely worth the wait.
Without the help of Dr Bains and Harpal Clinic, I would not have made this breakthrough.”

— P.C

The Harpal way

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We can provide low dose naltrexone (LDN) as an adjunct to your current management by your doctors. Please assume a minimum of 3 months of being on LDN before you start to notice a difference if any, although in the majority of people, this can be much sooner. A small number of people do not find that LDN makes much of a difference, and there is no way of knowing if you will respond favourably to LDN.

Where possible, we ask for:

  • Your primary carer (GP or specialist) is aware and supportive of you being here (not compulsory)
  • You have blood results within the past 3 months (not compulsory)
  • You bring in other relevant investigations that you have done, e.g. imaging reports etc. (not compulsory)

Whilst this is not strictly necessary, we prefer to work with your main doctors as LDN is still in its infancy.

We prefer to do a comprehensive consultation as most long term illnesses have many different causes for them, and our multidisciplinary approach tackles things in a stepwise fashion. However, we are aware that the costs involved can be prohibitive for many people, so we have designed a smaller, targeted focussed consultation which will mostly deal with the problem to hand.

We prefer to do face to face consultation but are also happy to do Facetime, Skype, or phone consults if that suits you better.

How do you take LDN?

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LDN is available in various forms:

  • Syrup – Good for when you initially start and are experimenting with different doses to find your dose. This is the most cost-effective option. It tastes like cough syrup. Contents: glycerol, base of linctus, sugarfree, natural colours (wild berry extract and paprika), star anise extract for flavour, trace of lactose.
  • Sublingual – Similar to syrup but preferable as it bypasses the gut absorption. This is our preferred option whilst you’re figuring out your dose. Most people continue to stay on this. Contents: cellulose, trace of lactose, glycerol.
  • Capsules – This is useful once you know your ideal dose as it can be made to any dose. Chemical and lactose-free.

LDN membership programme

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The initial consultation costs £195 with a monthly membership fee of £72.50 thereafter. This covers the cost of your subsequent follow-ups and prescription fees and medication. As a member, the following benefits are included for the duration of the programme:

✓ A 30-minute initial consultation.
✓ A doctor’s letter outlining your LDN treatment plan and any other suggestions made during the consultation.
✓ Fifteen-minute follow-up consultations after 3 months and then every 6 months thereafter.
✓ LDN medication delivered to your door.
✓ Telephone and email support for LDN related issues.
✓ Any members-only offers pertaining to other services provided by the clinic.

To join, email us at help@harpalclinic.co.uk or complete our Book An Appointment form.

Aaliyah, Harpal Clinic

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